2021-11-04 • Control for output spike rate

2021-11-04 • Control for output spike rate

We start by wanting a plot with output spike rate on the x-axis.

Prelude

from voltage_to_wiring_sim.notebook_init import *
Preloading: numpy, numba, matplotlib.pyplot, seaborn.
Importing from submodules … ✔
Imported `np`, `mpl`, `plt`, `sns`, `pd`
Imported codebase (`voltage_to_wiring_sim`) as `v`
Imported `*` from `v.support.units`
Setup autoreload
v.print_reproducibility_info()

This cell was last run by lpxtf3 on DUIP74576 on Thu 04 Nov 2021, at 17:24 (UTC+0000).
Last git commit (Thu 04 Nov 2021, 16:37). Uncommited changes to 4 files.

Output rate vs performance

from voltage_to_wiring_sim.experiments.N_to_1_IE import Params, simulate_and_test_connections, eval_performance
base_params = Params(p_inhibitory=0.2)
v.pprint(base_params)
Params
------
     sim_duration = 600
         timestep = 0.0001
       spike_rate = 20
           Δg_syn = 8E-10
            τ_syn = 0.007
    neuron_params = {'C': 1e-10, 'a': 30.0, 'b': -2e-09, 'c': -0.05, ...}
imaging_spike_SNR = 20
          v_syn_E = 0
          v_syn_I = -0.07
 num_spike_trains = 30
     p_inhibitory = 0.2
      p_connected = 0.6
  window_duration = 0.1
         rng_seed = 0
@v.cache_to_disk("2021-11-04__control_for_output_rate")
def sim_test_eval(params: Params):
    
    sim_data, _, test_summaries = simulate_and_test_connections(params)
    evalu_p_0_05, _, AUC, AUC_exc, AUC_inh = eval_performance(sim_data, test_summaries)
    
    output_spike_rate = sim_data.izh_output.spike_times.size / params.sim_duration
    
    return (output_spike_rate,
            evalu_p_0_05.TPR, evalu_p_0_05.TPR_exc, evalu_p_0_05.TPR_inh,
            AUC, AUC_exc, AUC_inh)
dgsyns = 0.8 * nS * np.logspace(-1, 1, num=11);
from dataclasses import replace
from joblib import Parallel, delayed
%%time
results = Parallel(n_jobs=-1)(delayed(sim_test_eval)(replace(base_params, Δg_syn=dg)) for dg in dgsyns);

3m49 without joblib parallel,
[1m26, 1m15] with.
1m14 with numba.set_num_threads(2) in addition.

(output_spike_rate,
 TPR, TPR_exc, TPR_inh,
 AUC, AUC_exc, AUC_inh) = zip(*results)

plt.plot(dgsyns, AUC, ".-");
plt.plot(dgsyns, AUC_exc, ".-");
plt.plot(dgsyns, AUC_inh, ".-");
../_images/2021-11-04__control_for_output_rate_14_0.png
plt.plot(output_spike_rate, AUC, ".-");
../_images/2021-11-04__control_for_output_rate_15_0.png
plt.plot(dgsyns, output_spike_rate, ".-");
../_images/2021-11-04__control_for_output_rate_16_0.png

To explore signals

sim_and_test = v.cache_to_disk(simulate_and_test_connections);
d, td, ts = sim_and_test(base_params);

Reproducibility

v.print_reproducibility_info(verbose=True)

This cell was last run by lpxtf3 on DUIP74576
on Thu 28 Oct 2021, at 15:09 (UTC+0100).

Last git commit (Thu 28 Oct 2021, 14:11).

Uncommited changes to:

 M notebooks/2021-09-16__vary_E_vs_I.ipynb

Platform:

Windows-10
CPython 3.9.6 (C:\miniforge3\python.exe)
Intel(R) Xeon(R) W-2123 CPU @ 3.60GHz

Dependencies of voltage_to_wiring_sim and their installed versions:

numpy                1.21.1
matplotlib           3.4.2
numba                0.53.1
joblib               1.0.1
seaborn              0.11.1
scipy                1.7.0
preload              2.2
nptyping             1.4.2

Full conda list:

# packages in environment at C:\miniforge3:
#
# Name                    Version                   Build  Channel
argon2-cffi               20.1.0           py39hb82d6ee_2    conda-forge
async_generator           1.10                       py_0    conda-forge
attrs                     21.2.0             pyhd8ed1ab_0    conda-forge
backcall                  0.2.0              pyh9f0ad1d_0    conda-forge
backports                 1.0                        py_2    conda-forge
backports.functools_lru_cache 1.6.4              pyhd8ed1ab_0    conda-forge
bleach                    3.3.1              pyhd8ed1ab_0    conda-forge
brotlipy                  0.7.0           py39hb82d6ee_1001    conda-forge
ca-certificates           2019.11.28           hecc5488_0    conda-forge/label/cf202003
certifi                   2021.10.8        py39hcbf5309_0    conda-forge
cffi                      1.14.6           py39h0878f49_0    conda-forge
chardet                   4.0.0            py39hcbf5309_1    conda-forge
charset-normalizer        2.0.0              pyhd8ed1ab_0    conda-forge
click                     7.1.2                    pypi_0    pypi
colorama                  0.4.4              pyh9f0ad1d_0    conda-forge
conda                     4.10.3           py39hcbf5309_2    conda-forge
conda-package-handling    1.7.3            py39hb3671d1_0    conda-forge
cryptography              3.4.7            py39hd8d06c1_0    conda-forge
cycler                    0.10.0                   pypi_0    pypi
debugpy                   1.4.1            py39h415ef7b_0    conda-forge
decorator                 5.0.9              pyhd8ed1ab_0    conda-forge
defusedxml                0.7.1              pyhd8ed1ab_0    conda-forge
entrypoints               0.3             pyhd8ed1ab_1003    conda-forge
icu                       68.2                 h0e60522_0    conda-forge
idna                      3.1                pyhd3deb0d_0    conda-forge
importlib-metadata        4.6.1            py39hcbf5309_0    conda-forge
ipykernel                 6.0.3            py39h832f523_0    conda-forge
ipython                   7.25.0           py39h832f523_1    conda-forge
ipython_genutils          0.2.0                      py_1    conda-forge
jedi                      0.18.0           py39hcbf5309_2    conda-forge
jinja2                    3.0.1              pyhd8ed1ab_0    conda-forge
joblib                    1.0.1                    pypi_0    pypi
jpeg                      9d                   h8ffe710_0    conda-forge
jsonschema                3.2.0              pyhd8ed1ab_3    conda-forge
jupyter_client            6.1.12             pyhd8ed1ab_0    conda-forge
jupyter_contrib_core      0.3.3                      py_2    conda-forge
jupyter_contrib_nbextensions 0.5.1              pyhd8ed1ab_2    conda-forge
jupyter_core              4.7.1            py39hcbf5309_0    conda-forge
jupyter_highlight_selected_word 0.2.0           py39hcbf5309_1002    conda-forge
jupyter_latex_envs        1.4.6           pyhd8ed1ab_1002    conda-forge
jupyter_nbextensions_configurator 0.4.1            py39hcbf5309_2    conda-forge
jupyterlab_pygments       0.1.2              pyh9f0ad1d_0    conda-forge
jupytray                  0.7                      pypi_0    pypi
kiwisolver                1.3.1                    pypi_0    pypi
libclang                  11.1.0          default_h5c34c98_1    conda-forge
libiconv                  1.16                 he774522_0    conda-forge
libpng                    1.6.37               h1d00b33_2    conda-forge
libsodium                 1.0.18               h8d14728_1    conda-forge
libxml2                   2.9.12               hf5bbc77_0    conda-forge
libxslt                   1.1.33               h65864e5_2    conda-forge
libzlib                   1.2.11            h8ffe710_1013    conda-forge
llvmlite                  0.36.0                   pypi_0    pypi
lxml                      4.6.3            py39h4fd7cdf_0    conda-forge
markupsafe                2.0.1            py39hb82d6ee_0    conda-forge
matplotlib                3.4.2                    pypi_0    pypi
matplotlib-inline         0.1.2              pyhd8ed1ab_2    conda-forge
menuinst                  1.4.17           py39hcbf5309_1    conda-forge
miniforge_console_shortcut 2.0                  h57928b3_0    conda-forge
mistune                   0.8.4           py39hb82d6ee_1004    conda-forge
nbclient                  0.5.3              pyhd8ed1ab_0    conda-forge
nbconvert                 6.1.0            py39hcbf5309_0    conda-forge
nbformat                  5.1.3              pyhd8ed1ab_0    conda-forge
nest-asyncio              1.5.1              pyhd8ed1ab_0    conda-forge
notebook                  6.4.0              pyha770c72_0    conda-forge
nptyping                  1.4.2                    pypi_0    pypi
numba                     0.53.1                   pypi_0    pypi
numpy                     1.21.1                   pypi_0    pypi
openssl                   1.1.1l               h8ffe710_0    conda-forge
packaging                 21.0               pyhd8ed1ab_0    conda-forge
pandas                    1.3.1                    pypi_0    pypi
pandoc                    2.14.1               h8ffe710_0    conda-forge
pandocfilters             1.4.2                      py_1    conda-forge
parso                     0.8.2              pyhd8ed1ab_0    conda-forge
pickleshare               0.7.5                   py_1003    conda-forge
pillow                    8.3.1                    pypi_0    pypi
pip                       21.2.1             pyhd8ed1ab_0    conda-forge
preload                   2.2                      pypi_0    pypi
prometheus_client         0.11.0             pyhd8ed1ab_0    conda-forge
prompt-toolkit            3.0.19             pyha770c72_0    conda-forge
pycosat                   0.6.3           py39hb82d6ee_1006    conda-forge
pycparser                 2.20               pyh9f0ad1d_2    conda-forge
pygments                  2.9.0              pyhd8ed1ab_0    conda-forge
pyopenssl                 20.0.1             pyhd8ed1ab_0    conda-forge
pyparsing                 2.4.7              pyh9f0ad1d_0    conda-forge
pyqt                      5.12.3           py39hcbf5309_7    conda-forge
pyqt-impl                 5.12.3           py39h415ef7b_7    conda-forge
pyqt5-sip                 4.19.18          py39h415ef7b_7    conda-forge
pyqtchart                 5.12             py39h415ef7b_7    conda-forge
pyqtwebengine             5.12.1           py39h415ef7b_7    conda-forge
pyrsistent                0.17.3           py39hb82d6ee_2    conda-forge
pysocks                   1.7.1            py39hcbf5309_3    conda-forge
python                    3.9.6           h7840368_1_cpython    conda-forge
python-dateutil           2.8.2              pyhd8ed1ab_0    conda-forge
python_abi                3.9                      2_cp39    conda-forge
pytz                      2021.1                   pypi_0    pypi
pywin32                   300              py39hb82d6ee_0    conda-forge
pywinpty                  1.1.3            py39h99910a6_0    conda-forge
pyyaml                    6.0              py39hb82d6ee_0    conda-forge
pyzmq                     22.1.0           py39he46f08e_0    conda-forge
qt                        5.12.9               h5909a2a_4    conda-forge
requests                  2.26.0             pyhd8ed1ab_0    conda-forge
ruamel_yaml               0.15.80         py39hb82d6ee_1004    conda-forge
scipy                     1.7.0                    pypi_0    pypi
seaborn                   0.11.1                   pypi_0    pypi
send2trash                1.7.1              pyhd8ed1ab_0    conda-forge
setuptools                49.6.0           py39hcbf5309_3    conda-forge
six                       1.16.0             pyh6c4a22f_0    conda-forge
sqlite                    3.36.0               h8ffe710_0    conda-forge
terminado                 0.10.1           py39hcbf5309_0    conda-forge
testpath                  0.5.0              pyhd8ed1ab_0    conda-forge
tornado                   6.1              py39hb82d6ee_1    conda-forge
tqdm                      4.61.2             pyhd8ed1ab_1    conda-forge
traitlets                 5.0.5                      py_0    conda-forge
typish                    1.9.2                    pypi_0    pypi
tzdata                    2021a                he74cb21_1    conda-forge
ucrt                      10.0.20348.0         h57928b3_0    conda-forge
urllib3                   1.26.6             pyhd8ed1ab_0    conda-forge
vc                        14.2                 hb210afc_5    conda-forge
voltage-to-wiring-sim     0.1                       dev_0    <develop>
vs2015_runtime            14.29.30037          h902a5da_5    conda-forge
wcwidth                   0.2.5              pyh9f0ad1d_2    conda-forge
webencodings              0.5.1                      py_1    conda-forge
wheel                     0.36.2             pyhd3deb0d_0    conda-forge
win_inet_pton             1.1.0            py39hcbf5309_2    conda-forge
wincertstore              0.2             py39hcbf5309_1006    conda-forge
winpty                    0.4.3                         4    conda-forge
winshell                  0.6                      pypi_0    pypi
yaml                      0.2.5                he774522_0    conda-forge
zeromq                    4.3.4                h0e60522_0    conda-forge
zipp                      3.5.0              pyhd8ed1ab_0    conda-forge
zlib                      1.2.11            h8ffe710_1013    conda-forge